If your loved one has moderate to severe

Alzheimer’s disease, and is taking ARICEPT®

(donepezil HCl) 10 mg, they may benefit

from A RICEPT 23 mg.

ARICEPT 23 mg showed statistically

significant benefit over ARICEPT 10 mg

on slowing the progression of cognitive

symptoms, as shown in a large clinical study

in moderate to severe Alzheimer’s patients.

As Alzheimer’s progresses, acetylcholine, a

key chemical vital to brain function, declines.

ARICEPT 23 mg is thought to work by

increasing the amount of acetylcholine,

allowing more of this important chemical

to remain in the brain.

ARICEPT is a prescription medicine to treat

mild to moderate Alzheimer’s disease (5 mg

or 10 mg) and moderate to severe Alzheimer’s

disease (10 mg or 23 mg).

Although there’s no cure for Alzheimer’s,

studies have shown A RICEPT slowed the

progression of Alzheimer’s symptoms.

Visit aricept.com to learn more.

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ARICEPT is not for everyone, including

people who are allergic to any ingredients in

ARICEPT or to medicines that contain

piperidines. People at risk for stomach ulcers

or who take certain other medicines should tell

their doctor because serious stomach problems,

such as bleeding, may get worse.

ARICEPT may cause slow heartbeat and

fainting. This happens more often in people

with heart problems. Call the doctor right

away if the patient faints while taking

ARICEPT. Lung problems, including asthma,

may worsen with the use of ARICEPT.

ARICEPT may cause seizures and difficulty

passing urine. People of lower weight (those

weighing less than 121 lbs) may have increased

nausea, vomiting, and decreased weight when

taking ARICEPT 23 mg. Tell the doctor if

the patient will be having surgery, medical or

dental procedures requiring anesthesia while

taking ARICEPT.

Some people may have nausea, diarrhea,

difficulty sleeping, vomiting, or muscle cramps.

Some people may feel tired or may have loss of

appetite. In a study, many more people taking

ARICEPT 23 mg experienced nausea and

vomiting than those taking ARICEPT 10 mg.

These side effects may get better after the

patient takes ARICEPT for a while.

Please see important Patient Information on

next page. For more information, visit

aricept.com or call 1-866-4-A R IC E P T

You are encouraged to report negative side effects to the FDA. Visit fda.gov/medwatch

or call 1-800-FDA-1088.

ARICEPT® is a registered trademark of Eisai Co., Ltd. © 2010 Eisai Inc. and Pfizer Inc. All rights reserved.

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